Face à face
| Cuba - Campeonato Nacional | 2022/04/09 20:00 | Santiago Cuba v Guantanamo FC | L | 2-1 |
| Cuba - Campeonato Nacional | 2022/02/19 20:00 | Guantanamo FC v Santiago Cuba | W | 2-0 |
| Cuba - Campeonato Nacional | 2019/12/14 20:01 | Santiago Cuba v Guantanamo FC | L | 1-0 |
| Cuba - Campeonato Nacional | 2019/05/07 20:00 | Guantanamo FC v Santiago Cuba | L | 1-2 |
| Cuba - Campeonato Nacional | 2019/02/06 19:50 | Guantanamo FC v Santiago Cuba | L | 0-1 |
| Cuba - Campeonato Nacional | 2019/01/19 20:05 | Santiago Cuba v Guantanamo FC | D | 1-1 |
Home History
| Cuba - Campeonato Nacional | 2022/10/22 20:00 | Guantanamo FC v Villa Clara | W | 3-0 |
| Cuba - Campeonato Nacional | 2022/10/15 20:00 | La Habana v Guantanamo FC | L | 3-2 |
| Cuba - Campeonato Nacional | 2022/10/12 20:00 | Artemisa FC v Guantanamo FC | L | 2-0 |
| Cuba - Campeonato Nacional | 2022/09/17 20:00 | FC Cienfuegos v Guantanamo FC | D | 2-2 |
| Cuba - Campeonato Nacional | 2022/09/10 20:00 | Guantanamo FC v Camaguey | L | 0-2 |
| Cuba - Campeonato Nacional | 2022/05/07 20:00 | Guantanamo FC v Sancti Spritus | W | 3-0 |
| Cuba - Campeonato Nacional | 2022/04/30 20:00 | Guantanamo FC v Camaguey | D | 0-0 |
| Cuba - Campeonato Nacional | 2022/04/09 20:00 | Santiago Cuba v Guantanamo FC | L | 2-1 |
Away History
| Cuba - Campeonato Nacional | 2022/10/22 20:00 | La Habana v Santiago Cuba | L | 2-1 |
| Cuba - Campeonato Nacional | 2022/10/15 20:00 | Santiago Cuba v FC Cienfuegos | D | 1-1 |
| Cuba - Campeonato Nacional | 2022/10/12 20:00 | Santiago Cuba v Camaguey | W | 2-1 |
| Cuba - Campeonato Nacional | 2022/10/08 20:04 | Santiago Cuba v Artemisa FC | W | 5-0 |
| Cuba - Campeonato Nacional | 2022/05/15 20:00 | Santiago Cuba v Artemisa FC | W | 7-0 |
| Cuba - Campeonato Nacional | 2022/04/30 20:19 | Santiago Cuba v Ciego de Avila | W | 4-0 |
| Cuba - Campeonato Nacional | 2022/04/23 20:00 | Granma v Santiago Cuba | W | 2-3 |
| Cuba - Campeonato Nacional | 2022/04/16 20:00 | Santiago Cuba v Camaguey | W | 4-1 |